Hyperthyroidism in children mostly Graves’ disease, which is an autoimmune disease, caused by TSH receptor autoantibodies (TRAb) stimulates thyroid cells increase the synthesis and release of thyroid hormones in the blood, causing symptoms thyrotoxicosis does. Through the effects of TRAb on thyroid cells and some other organizations, autoantibodies TRAb decided the synthesis and release of thyroid hormones in the blood, causing an autoimmune manifestations clinically characterized as ocular signs, consistent posting. affect the severity, the disease lightly. TRAb increase in 95-100% Graves’ disease patients at the time of diagnosis.