The important role of active compounds from natural products from various sources especially derived from plants, has been confirmed from the folk medicine to modern medicine. Their effects are not only used directly as a folk medicine but as a prototype or an inportant role for the discovery and development of new drugs. Vietnam is rich a country in medicinal resources, which has a high potential of medicinal plants and has a lot of experience using this source of medication by its long tradition of medicine. According to Dictionary of Vietnamese medicinal plants, in Vietnam, there were 13000 species, in which 5000 species were used to folk medicine. This is the suggestions for us to study this source of medicine for the life. In the course of screening program of extracts from Vietnam medicinal plants with cytotoxic and anti-inflammatory activities, the methanolic extract of the tubers of O. japonicus showed significant cytotoxic and anti-inflammatory effects and was chosen for further in continuing studies of this thesis