Vietnam has 54 ethnic groups such as: Kinh, Tay, Dao, San Chay, Mong, Nung, San Diu, E de. Some ethnic groups have precious medicinal plants, valuable traditional treatment and therapeutic remedies trusted by the people and recognized by the Oriental Medicine Association of Vietnam. However people’s medicine has not been proven in science. Vietnam is located in tropical monsoon climate zone, so the country’s vegetation is rich and diversified, Vietnam has many natural conservations that are home to thousands of species of rare plants and animals, and rich medicinal herbs and various resources. Species Balanophora laxiflora Hemsly and Ficus hirta Vahl, are precious medicinal plants in the treasure herbs, medicinal Vietnam, species B.laxiflora and species F. hirta has been used in traditional medicine Vietnam for treatment of various diseases such as: a tonic for blood circulation improvement, recovery, antipyretic, antidote, appetite stimulation, Recent researchers have discovered various compounds and bioactivities of B. laxiflora. For instance, antioxidant hydrolysable tannins with a phenylacrylic acid derivative such as caffeoyl, coumaroyl, anti-inflammatory metabolites, hypouricemic activity.Study on chemical constituents and biological activity of two species Balanophora laxiflora Hemsl and Ficus hirta Vahl are necessary, in order to elucidate biochemical and bioactive significance as well as extend the use of species Balanophora laxiflora Hemsl and Ficus hirta Vahl, we carry out the topic:”Study on chemical constituents and biological activity of Balanophora laxiflora Hemsl. and Ficus hirta Vahl.